Fibric Acid Antilipemic Agents

Overview

4.6 out of 5 (30 Reviews)

Credits

1.50

Pharmacology Credits

1.50

Post-Assessment Questions

7

Start Date

1 Sep 2023

Last Review Date

2 Aug 2025

Expiration Date

31 Aug 2026

Estimated Time To Finish

90 Minutes


Unlimited Nurse Practitioner CE

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Activity Description

Fibric acid derivatives, or fibrates, are lipid-lowering agents approved for treating primary hypercholesterolemia and mixed dyslipidemia. As agonists of peroxisome proliferator-activated receptor alpha, fibrates reduce triglycerides and modestly increase high-density lipoprotein cholesterol, offering therapeutic benefits in patients with severe hypertriglyceridemia or atherogenic dyslipidemia. Despite their utility, fibrates are underprescribed due to concerns over potential adverse effects—particularly myopathy when used with statins—and limited clinician familiarity with patient selection, drug monitoring, and the United States Food and Drug Administration-labeled versus off-label indications. Fibrates are recommended in conjunction with dietary and lifestyle modifications and are used in clinical scenarios ranging from cardiovascular risk management to triglyceride-induced pancreatitis prevention.

This educational activity enhances clinician competence in identifying appropriate candidates for fibrate therapy, applying evidence-based treatment protocols, and managing drug interactions and monitoring requirements. Clinicians gain practical tools to balance benefits and risks, especially when combining fibrates with other lipid-lowering agents. Interprofessional collaboration among physicians, pharmacists, nurses, and dietitians improves medication safety, reinforces adherence to dietary interventions, and ensures timely monitoring. Team-based care contributes to optimized lipid control, reduced treatment complications, and improved cardiovascular outcomes in high-risk patient populations.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify patients with primary hypercholesterolemia or mixed dyslipidemia who are appropriate candidates for fibric acid therapy.

  • Assess for signs of myopathy, hepatotoxicity, and gallstone risk (especially when used with statins) in patients who are on fibric acid therapy.

  • Screen for contraindications, such as hepatic or severe renal impairment, before initiating therapy with fibric acid derivatives.

  • Implement effective collaboration and communication among interprofessional team members to enhance outcomes and treatment efficacy for patients who may benefit from fibric acid pharmacotherapy.

  • Outline the indications of Fibric Acid Antilipemic Agents

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurse Practitioners: StatPearls designates this activity for 1.50 ANCC contact hour(s), which includes 1.50 hour(s) of pharmacology. NPs should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the FDA. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Deborah Z. on 11/3/2021

Mary Y. on 11/14/2021

christopher k. on 8/29/2022

Stephanie C. on 1/29/2023

Joanne S. on 3/12/2023

Quarshiwaa A. on 4/10/2023

Meagan K. on 6/3/2023

Amy G. on 8/3/2023

Megan T. on 9/19/2023

Kathleen on 10/8/2023

Mackenzie H. on 10/19/2023

Daniel T. on 10/29/2023

NO A. on 11/5/2023

Robert R. on 1/10/2024

Michael F. on 1/22/2024

Mohamad K. on 3/25/2024

Kristine G. on 4/4/2024

Lindsey A. on 4/5/2024

Thomas P. on 5/4/2024

Chandler P. on 5/10/2024

Stephanie H. on 5/15/2024

Zachariah Z. on 6/24/2024

Michael S. on 8/29/2024

Mary Y. on 9/20/2024

Lauren M. on 10/14/2024

Megan G. on 11/10/2024

Luke F. on 11/30/2024

Natalie M. on 12/31/2024

John P. on 1/6/2025

Emily C. on 7/21/2025

Unlimited Nurse Practitioner CE

Stay up to date on the latest medical knowledge with 6689 CE activities. In these online self-assessment activities, read our reference articles and test your knowledge with more than 7956.5 hours of CE.

Single Activity

Take this single activity

$73.50 1 activity

6 Month Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$299 per half year per user

1 Year Unlimited Nurse Practitioner CE

Access to all the Unlimited Nurse Practitioner CE activities in all specialties.

$479 per 1 year per user